This chapter makes the case for nexus thinking in the study of the international political economy of energy and resources, that is their inter-dependencies with other policy areas. It argues that it is imperative to go beyond an IPE of ‘just energy’ – rather than treating it as truly ‘discrete’ – to understand energy and resources as part of dynamic inter-relationship with other issue areas. In addition to the ones related to climate change, security and development, nexuses as identified in the chapter include the energy–technology nexus, the energy–water nexus, the energy–food nexus, or the global–local nexus in energy, all of which are increasingly identified within some global and national governance organisations and within recent scholarship. The chapter suggests that from a scholarly point of view this establishes energy as a highly complex, interconnected policy area – both in terms of how energy markets and technical regimes are constituted, their implications for other issue areas, and in terms of the extent to which governance institutions are being designed that stretch across these issue areas. Moreover, the chapter makes the case for the ‘IPE toolkit’ being well equipped to capture energy nexuses in their various forms and shapes. Finally, the chapter lays out the structure and the content of the Handbook.