This chapter examines the place of the neighbourhood in relation to entrepreneurial processes. It explores these processes from the perspective of research on housing and neighbourhoods, and it does so with a particular interest in more deprived neighbourhoods and the potential for entrepreneurial activities to contribute to the regeneration of these locations. The chapter argues that the neighbourhood retains an important place in daily lives as a realm of social interaction and relationships. It explores how the neighbourhood may influence entrepreneurial processes in a number of ways. It looks at the neighbourhood as a potential influence on attitudes to entrepreneurship and the decision to start a business, and in terms of the environment or resources it provides for entrepreneurial success, including resources accessed through social capital or networks. It also examines how entrepreneurial concerns may impact on neighbourhood choice and hence the consequences for sorting processes. In relation to more deprived neighbourhoods, it argues that it is difficult to avoid the general conclusion that these have not only less entrepreneurial potential by virtue of the population, but also a more difficult environment. Nevertheless, it concludes that we should not understate the importance or the potential of entrepreneurial activities for deprived neighbourhoods, and that we should recognise diverse forms of entrepreneurship which are already an asset in these areas.