Developing countries are increasingly important in the global economy and levels of trade and foreign direct investment (FDI) between developed and developing countries are expanding. This chapter argues that increasing levels of trade and investment results in greater numbers of expatriates to/from developed/developing countries. The literature on developing countries remains limited and this is the case relative to expatriates, therefore little is known about expatriates moving between the two groups of countries. This chapter discusses the limited literature on expatriates to/from developed/developing countries. It briefly considers the need for expatriates in the context of FDI and gives evidence of the growth in FDI between developed and developing countries. It considers differences between the two sets of countries as background to examining the literature on expatriates in this context. The chapter concludes with suggestions for areas of research and acknowledges that this is an extremely important and relevant area for research. Academics are encouraged to consider it as a fertile research field.