Mental health problems represent a growing work-related issue, with far-reaching impacts on workers, their families, employers and communities. Some professions, including veterinarians and veterinary nurses, are at a particular high risk of workplace mental health problems. This chapter adapts generic strategies for responding to workplace mental health problems to the specific needs of the veterinary sector as part of a broader study to show how guidelines can be tailored to suit the needs of specific occupational groups. Thirty veterinary professionals were consulted to discuss factors contributing to suicide and mental health problems amongst veterinary professions, factors that promote mental health, prevention strategies, and the short-, medium- and long-term actions that organizations could implement to address issues in different veterinary work settings. This information may be used to support veterinary workplaces to respond to work-related mental health problems that have been found to be highly prevalent in the veterinary context.