This chapter analyzes the public policy trajectory in promoting science, technology and innovation (STI) in healthcare in Brazil during the period 2002–14. Specifically, it shows how STI policies have incorporated the promotion of healthcare issues and how such incorporation could be related to inclusive development strategies. To do so, the chapter first explores relevant theoretical perspectives on the relation between STI policies and inclusive development objectives. Then, based on the analysis of the official documents and twenty semi-structured interviews with policymakers and healthcare scholars, the chapter explores public policy trajectory through the evolution of the health issues in STI priority areas and the progress of interactions among healthcare, science-technology, and the production–innovation sub-systems of the economy. Based on conceptual and empirical exploration, the chapter assesses the STI policy orientation towards inclusive development strategies and draws attention to the key role of healthcare and STI policies working together to attend to the needs of the Brazilian healthcare system.