Experimental economics offers useful tools for cross-cultural research. Experimental games are well-defined environments characterized by a set of players, strategies and incentives. Conducting identical experiments with subjects from different cultures offers unprecedented control over the environment in which behavior is observed. Nevertheless, cross-cultural experimentation poses a number of methodological challenges, because culture cannot be randomly assigned to participants. This chapter provides an outline of how experimental games may be used to measure culture, followed by a review and discussion of the methods used in cross-cultural behavioral experiments. The chapter surveys the literature on cross-cultural experiments and offers a re-analysis of cross-cultural data sets to quantify the importance of cultural variation relative to subject pool variation.