New technology-based ﬁrms (NTBFs) are an important source of new jobs and play a crucial role in economic growth. In carrying out their ‘third mission’ of fostering links with knowledge users and facilitating technology transfer, entrepreneurial universities can contribute substantially to the creation of NTBFs. In this chapter the authors applied panel data random effect models to a sample drawn from 65 countries over the period 2006_13 to analyse the extent to which entrepreneurial universities drive technology entrepreneurship (TE). Their results showed that ‘university_industry relationship’ had a positive effect on TE, whereas ‘entrepreneurship education in business schools’ did not. This evidence on universities’ interactions with industry corroborates the knowledge spillover theory of entrepreneurship. The authors propose specific mechanisms that policy makers could use to increase university_industry collaboration.