In-work poverty became a prominent policy issue in the United States (US) long before the term itself acquired any meaning and relevance in other industrialized countries. With the US’s embrace of an employment-centered anti-poverty strategy, in-work poverty has become even more of an issue. This chapter reviews some key trends, drivers and policy issues. How much in-work poverty is there in the US? How does the US compare to other rich democracies? Has the US’s in-work poverty rate changed over time? Who are the in-work poor? What are the main drivers of levels and changes in in-work poverty? Finally, what are the prospects for the US’s working poor going forward?