The transformations brought about by the globalization of the world of work render insufficient the national efforts to face a cross-boundaries phenomenon. Similarly, the International Labour Organization efforts are praiseworthy but incomplete because its Members are reluctant to enter new international commitments. In this situation, labor human rights are in the best position to face the challenges of globalization. The Inter-American System of Human Rights has been playing an important role is protecting labor rights in the American hemisphere. However, labor lawyers usually favor the role of ILO supervisory bodies in the field of international labour law, therefore paying little attention to this system. This could, perhaps, be explained by the lack of knowledge among labor lawyers on how the system operates. This chapter tries to bridge this gap in order to integrate the Inter-American System into the international labour law analysis framework by analysing the judgments of Inter-American Court of Human Rights.