Lesbian, gay, bisexual, transgender, queer or questioning and intersex (LGBTQI) employees make up a significant constituency within the workforce. Yet, career concerns and challenges pertaining to diversity on the basis of sexuality and gender identity have traditionally been neglected in the wider career development literature. This chapter explores both the constraints faced by sexuality and gender identity minority employees in planning and developing their careers, and also the possible remedial actions which are uniquely tailored to LGBTQI workers in order to ensure that organizations are sufficiently equipped to respond to the pressing needs of their diverse workforce. Therefore, the goal of the authors is to elucidate the current career challenges and possible pathways of improvement for the LGBTQI workers. They first provide an overview of the existing research, theories and concepts that shed light on the career outcomes of LGBTQI employees; then they identify and discuss recommendations for policy and practice.