Nature plays an important role in addressing the risks posed by climate change. In this chapter, the authors explore nature’s contribution to improving micro-climatic conditions in cities and mitigating urban heat stress, thereby helping cities become climate resilient. Green infrastructure, such as parks and tree-lined streets, can contribute to climate resilience and the health of urban populations by reducing heat stress, as well as hospitalisations and mortality. Today, with more than half of the global population urbanised, population densities and the heat island effect amplify heat-related risks in cities and necessitate appropriate solutions. The chapter presents a range of examples illustrating the benefits of nature, building mainly on insights from Europe. It also details how stakeholders collaborate to invest in urban and suburban green infrastructure and use a variety of tools, measures, processes and financing sources. The chapter then outlines a road map for moving forward.