Global trade is impossible without transportation, making efficient transport a key trade facilitator. Increasing the efficiency of transport and lowering the associated freight and time costs are key fields for action in view of lowering trade costs, and thus enhance global trade. This chapter discusses the transport networks and transport modes that support global trade. The chapter first discusses the changes in the appearance of goods traded worldwide and the impacts of these changes on the increasing scale and segmentation in the transport industry. Next it provides an analysis of the design and function of transport networks, following a four-layer approach (i.e. location, infrastructure, transport operations and logistics organization). The chapter then provides further detailed elaboration on each of these layers, before presenting some concluding remarks.