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Handbook of Research on Techno-Entrepreneurship

Edited by François Thérin

Techno-entrepreneurship is broadly defined as the entrepreneurial and intrapreneurial activities of both existing and nascent companies operating in technology-intensive environments. Boasting rich conceptual and empirical contributions by leading international specialists, this highly original Handbook will prove an invaluable tool in advancing our understanding of the theory and practice of research in this emerging area. The expert contributors initially explore the foundations of the field, clearly defining the parameters of techno-entrepreneurship.
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Chapter 15: Small Businesses for High Targets: Strategies in Industrially Exploiting the DNA–RNA Biomechanisms

Nicola Dellepiane


Nicola Dellepiane Entrepreneurship in the DNA–RNA Area Virtually all pathological processes in animal and vegetal life are associated with underproduction or overproduction of proteins or production of wrong proteins. Each process is also characterized by specific complex pathways, at molecular level, very difficult to unravel. The pathological aspects tied to, overproduction or underproduction or wrong production of proteins, instead, have been more easily grasped and research has therefore concentrated its efforts to find ways of correcting them. Recombinant technologies, the breakthrough that started the biotechnogenetic revolution, have made possible the production of large quantities of proteins with potential uses to correct the pathological imbalances mentioned above. A number of small dedicated biotech firms started the industrial utilization of recombinant DNA (r-DNA) in the late 1970s. Large companies, mainly operating in human and animal pharmaceuticals and diagnostics, and in animal breeding and agriculture, soon entered the game. Their strategies have aimed at ensuring that the new biotech products could not too quickly weaken the standing of their present products, well positioned in the market. At the same time, they have tried to establish an important presence in controlling the speed and direction of exploitation of the new technologies without excessively exposing themselves to risk. It has been relatively easy for them to capitalize on, sometimes only temporary, weak moments of the young biotech firms, to gain positions of strength that have curbed small biofirms’ competitive relevance. Biotech start-ups have been initiated by bioscientists who contributed with...

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