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Edited by Graeme A. Hodge, Diana M. Bowman and Andrew D. Maynard
Chapter 7: The Current Risk Assessment Paradigm in Relation to the Regulation of Nanotechnologies
Qasim Chaudhry, Hans Bouwmeester and Rolf F. Hertel 7.1 INTRODUCTION It has been suggested for some time that manipulating properties of materials at a small size scale may open up new opportunities for development of new functionalities (Feynman, 1959). The recent advent of nanotechnology has provided a systematic approach to the study and use of material properties in the size range close to the molecular level. Understanding the properties of materials at nanoscale provides opportunities for ‘finetuning’ of certain properties, as well as development of novel functionalities for specific applications. Due to the cross-cutting and enabling nature, applications of nanotechnology already span a vast range of industrial and consumer sectors. Of particular interest in this regard are engineered nanomaterials (ENMs) that are manufactured specifically to achieve a certain property or a composition. In many products and applications, ENMs are incorporated in fixed, bound or embedded forms, such as plastic materials for packaging. Other applications, such as certain cosmetics and personal care products, may contain free engineered nanoparticles (ENPs).1 The fundamental drivers at the heart of most nanotechnology applications are their potential to enable a reduction in the use of chemical substances, and development of novel functionalities. Because of the very large surface to mass ratio (also termed as aspect ratio), a relatively small amount of an ENM may provide a level of functionality that would otherwise need a much greater amount of the conventional bulk2 equivalent. The very small size of ENMs may also offer further benefits. For example,...
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